Trimethoprim is a widely used antibiotic designed to treat bacterial infections, most notably urinary tract infections (UTIs). It works by inhibiting bacterial DNA synthesis, halting the growth of the bacteria responsible for the infection.
It is typically prescribed for short-term use in acute UTIs, particularly in women, but may also be used as a long-term prophylactic treatment for recurrent infections. Trimethoprim is also effective in certain respiratory or gastrointestinal infections when clinically indicated.
Standard formulations include 100mg (for prophylaxis) and 200mg (for active infection). For uncomplicated UTIs, it is commonly prescribed as 200mg twice daily for 3 days. In cases requiring extended coverage or prophylactic use, dosage and duration will be tailored by a GP.
Trimethoprim is well-absorbed and typically begins to relieve symptoms within the first 1–2 days of treatment. It is important to complete the entire prescribed course, even if symptoms resolve early, to prevent resistance and recurrence.
How It Works
Trimethoprim blocks the bacterial enzyme dihydrofolate reductase, essential for DNA replication. This action prevents bacteria from multiplying, allowing the immune system to eliminate the remaining infection.
Why Choose Trimethoprim
Rapid and reliable UTI symptom relief
Targeted action against most common urinary pathogens
Available in short-course or long-term prophylactic dosing
Trusted by GPs and widely used in UK healthcare settings
Important Note
Take Trimethoprim exactly as prescribed. It should be taken with water and can be taken with or without food. Ensure adequate fluid intake during treatment. Do not share with others, even if symptoms appear similar.
Report any rashes, fever, or unusual symptoms to a healthcare provider, particularly if you have a history of sulfa allergies or kidney/liver problems.
Directions
Note: Follow the leaflet and GP instructions carefully.
-
Standard adult dose: 200mg twice daily for 3 to 7 days for acute UTI
-
For prophylaxis: 100mg once daily at night (if prescribed)
-
Swallow tablets with water, with or without food
-
Complete the full course, even if symptoms resolve early
Storage:
Deprecated: Function wc_enqueue_js is
deprecated since version 10.4.0! Use wp_add_inline_script instead. in
/var/www/vhosts/pharmacymentordev.com/woopw-dev-himani.pharmacymentordev.com/wp-includes/functions.php on line
6170
Ingredients
Deprecated: Function wc_enqueue_js is
deprecated since version 10.4.0! Use wp_add_inline_script instead. in
/var/www/vhosts/pharmacymentordev.com/woopw-dev-himani.pharmacymentordev.com/wp-includes/functions.php on line
6170
Side Effects
Common side effects:
-
Nausea
-
Skin rash
-
Headache
-
Diarrhoea
Rare but serious:
Seek immediate advice if rash, jaundice, sore throat, or easy bruising occurs.
Deprecated: Function wc_enqueue_js is
deprecated since version 10.4.0! Use wp_add_inline_script instead. in
/var/www/vhosts/pharmacymentordev.com/woopw-dev-himani.pharmacymentordev.com/wp-includes/functions.php on line
6170
Warnings
-
Avoid if allergic to Trimethoprim or sulfonamides
-
Not routinely used during early pregnancy or folate deficiency
-
Use caution in renal or hepatic impairment
-
May interact with methotrexate, warfarin, or diuretics
Deprecated: Function wc_enqueue_js is
deprecated since version 10.4.0! Use wp_add_inline_script instead. in
/var/www/vhosts/pharmacymentordev.com/woopw-dev-himani.pharmacymentordev.com/wp-includes/functions.php on line
6170
-
Most people begin to feel better within 24 to 48 hours of starting the treatment. However, you should still complete the full course, even if symptoms improve early.
-
There’s no direct interaction between Trimethoprim and alcohol, but drinking may increase the risk of side effects like nausea. It’s best to avoid alcohol until you finish the course.
-
Take it as soon as you remember. If it’s nearly time for your next dose, skip the missed one — don’t double up. Always aim to take doses at evenly spaced intervals.
-
Yes, doctors may prescribe Trimethoprim for certain chest infections, especially if they’re caused by specific types of bacteria. Always follow medical advice for the best results.
-
Trimethoprim isn’t usually recommended during pregnancy, especially in the first trimester. If you’re pregnant or trying for a baby, speak to your doctor before taking it.
Deprecated: Function wc_enqueue_js is
deprecated since version 10.4.0! Use wp_add_inline_script instead. in
/var/www/vhosts/pharmacymentordev.com/woopw-dev-himani.pharmacymentordev.com/wp-includes/functions.php on line
6170