GPhC Registered Pharmacy — Verified & Trusted
Prescription Only

Lymecycline Capsules 408 mg

Lymecycline is a prescription-only oral antibiotic used once daily to treat moderate to severe acne and certain skin infections.

Starting from
£13.80£38.00

Price varies by strength. Includes prescription review.

Order within 0h 0m for next day delivery on all items
Start Assessment

By starting you agree to our Privacy Policy and confirm you are over 18.

Reviewed by UK-registered prescribers
Discreet next-day delivery
Ongoing clinical support included
GPhC-registered pharmacy

Lymecycline is a prescription-only oral antibiotic commonly used to treat acne vulgaris and other bacterial infections such as respiratory tract infections, urinary tract infections, and certain sexually transmitted diseases. It belongs to the tetracycline class of antibiotics and is especially valued for its efficacy in treating inflammatory acne that is resistant to topical therapies. Lymecycline is suitable for adolescents and adults, and it works best as part of a long-term acne management plan, often in combination with non-antibiotic treatments such as topical retinoids or benzoyl peroxide.

How It Works
Lymecycline works by inhibiting bacterial protein synthesis. It targets the 30S subunit of bacterial ribosomes, preventing bacteria from producing the proteins they need to grow and multiply. This bacteriostatic effect halts the spread of infection and allows the immune system to eliminate the remaining bacteria. In acne, Lymecycline is particularly effective at targeting Cutibacterium acnes, a bacteria involved in the development of inflamed spots, pustules, and nodules. As a systemic treatment, Lymecycline reduces bacterial levels deep within the skin and hair follicles, helping to decrease inflammation and clear up breakouts over time.

Why Choose Lymecycline
Lymecycline is often preferred over older tetracyclines due to its improved gastrointestinal tolerance and convenient once-daily dosing. It has a favourable absorption profile and causes fewer side effects compared to some other oral antibiotics. Its effectiveness in reducing moderate to severe acne lesions, particularly inflammatory types, makes it a key option in dermatological care. When combined with topical agents, Lymecycline can help achieve visible skin improvements within 6–12 weeks, improving confidence and quality of life for many patients. It is also useful in treating certain bacterial infections beyond dermatological use, offering flexibility for prescribers.

Important Note
Lymecycline should only be used under medical supervision and is not suitable for children under 12 years of age or during pregnancy and breastfeeding. It may reduce the effectiveness of oral contraceptives and should be used with caution in patients with liver or kidney impairment. It does not treat viral infections and should be taken as prescribed to prevent resistance. Avoid prolonged sun exposure while taking Lymecycline, as it may increase photosensitivity.

Directions

Always follow the patient information leaflet before use.

    • Adults and adolescents: Take 408 mg (one capsule) once daily, preferably after food, or as prescribed.

    • Administration: Swallow whole with a full glass of water; do not chew or lie down for at least 30 minutes.

    • Storage: Store below 25°C, in its original container; protect from moisture and light; keep out of reach of children.

    • Disposal: Return unused medication to a pharmacy.

Ingredients

  • Active Ingredient:

    • Lymecycline 408 mg (equivalent to tetracycline base 300 mg)

    Other Ingredients:

    • Magnesium stearate

    • Colloidal anhydrous silica

    • Gelatin

    • Titanium dioxide

    • Indigo carmine

    • Quinoline yellow

    • Erythrosine

Side Effects

Common Side Effects:

  • Nausea, gastrointestinal discomfort

  • Photosensitivity

  • Headache

Serious Side Effects:

  • Severe diarrhoea (possible antibiotic-associated colitis)

  • Allergic reactions (e.g. rash, swelling, difficulty breathing)

  • Intracranial hypertension (severe headache or vision changes)
    If you notice any symptoms, consult your GP or healthcare provider immediately.

Warnings

  • Contraindications: Allergy to tetracyclines; pregnancy and children under 12 due to effects on teeth and bone.

  • Cautions: People with liver or kidney impairment, and those with inflammatory bowel disease.

  • Pregnancy/Breastfeeding: Only use if clearly prescribed.

  • Drug Interactions: Avoid antacids, calcium, iron, magnesium within two hours; may reduce the effectiveness of oral contraceptives—use additional protection.

Can I combine Lymecycline with other medications?

You can often use topical acne treatments alongside Lymecycline, but always inform your healthcare provider about any other medicines or supplements you’re taking.

Yes, Lymecycline can be taken with or without food. However, taking it with a glass of water helps prevent irritation of the oesophagus.

Lymecycline typically starts to reduce inflammation and bacterial activity within 1–2 weeks, with noticeable improvement in acne over 6–8 weeks.

Lymecycline is not recommended during pregnancy or breastfeeding due to potential risks to the baby’s bone and teeth development.

Yes, Lymecycline is prescribed for daily use, often over a 6–12 week course. Your prescriber may adjust the duration based on your skin’s response.

How It Works

How it works

No GP appointment needed. Five simple steps to get your treatment delivered.

1

Start Consultation

Begin your online consultation by answering a short medical questionnaire about your health.

2

Choose Treatment

Select your preferred treatment from our range of clinically-approved options.

3

Prescribe

Our UK-registered prescriber reviews your consultation and issues a prescription if appropriate.

4

Review

Our pharmacist clinically checks your prescription and dispenses your medication safely.

5

Delivered to Your Door

Your medication is dispatched in discreet packaging with next-day delivery available.

Patient Reviews

Trusted by thousands

See what our patients are saying about their experience.

Best pharmacy service I've used. Properly supported with check-ins — not just a dispensing machine. Real clinical care.

MS
Mitesh S.Verified Patient

I was nervous about ordering online but the team were so professional and the consultation felt thorough. Highly recommend.

NH
Nicola H.Verified Patient

Incredibly smooth process from start to finish. Medication arrived the next day in discreet packaging. Will definitely use again.

GE
Gareth E.Verified Patient

Patient video stories

Real patients sharing their experience in their own words.

Who Are We

A pharmacy team you can trust

We’re a GPhC-registered pharmacy run by qualified pharmacists and independent prescribers. Every consultation is clinically reviewed — because your health is never just a transaction.

Clinically governed Every order reviewed by a qualified prescriber before dispensing.
Patient-first approach We treat patients, not orders. Clinical support throughout your treatment.
Transparent & compliant Fully compliant with GPhC, MHRA, and NHS standards.
Learn More About Us
Clinical Lead
Dispenser
Pharmacist 1
Pharmacist 2
Prescriber
Support Team

Ready to start your treatment?

Browse our treatments or book a consultation with our pharmacy team today.

Trusted By & Working With