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Protopic 0.1% Ointment

Protopic 0.1% Ointment is a non-steroidal treatment for moderate to severe eczema in adults and adolescents over 16 years.Packaging and branding may differ from image shown.

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Protopic 0.1% Ointment is a prescription-only topical treatment used to manage moderate to severe atopic dermatitis (eczema) in adults and adolescents aged 16 and over. It is especially useful for individuals who have not responded adequately to conventional therapies, such as topical corticosteroids. Atopic dermatitis is a chronic inflammatory skin condition characterised by intense itching, redness, and skin thickening, often leading to flare-ups that significantly impact quality of life. Protopic provides an effective, non-steroidal alternative for long-term symptom control and flare-up prevention.

How It Works

Protopic contains the active ingredient tacrolimus, which belongs to a class of medicines known as calcineurin inhibitors. Tacrolimus works by suppressing the immune response in the skin that triggers inflammation. In patients with eczema, the immune system overreacts to irritants, resulting in inflamed and itchy skin. Tacrolimus blocks the activation of T-cells and the release of pro-inflammatory substances such as cytokines, reducing redness, swelling, and itching. Unlike corticosteroids, tacrolimus does not thin the skin, making it safe for long-term use and suitable for delicate areas like the face, neck, and folds of the skin.

Why Choose Protopic 0.1% Ointment

Protopic 0.1% is often recommended when other treatments have not worked or are not well tolerated. Its benefits include:

  • Non-steroidal formula: Reduces inflammation without the side effects associated with prolonged steroid use.

  • Targeted relief: Effectively manages flare-ups and provides sustained control of eczema symptoms.

  • Maintenance treatment: Can be used twice weekly as part of a proactive regimen to prevent relapses.

  • Skin barrier support: Helps restore and maintain healthy skin, reducing the cycle of itching and scratching.

This formulation is intended for adults and adolescents aged 16 years and above. A lower strength (0.03%) is typically prescribed for children.

Important Note

Protopic 0.1% should be applied in a thin layer to the affected areas as directed by your healthcare provider. It is not for use on infected skin or open wounds. Temporary burning or itching at the application site is common but usually subsides with continued use. Avoid sunlight and UV light exposure during treatment, and do not use tanning beds. Protopic is not a cure for eczema but can significantly reduce the severity and frequency of flare-ups when used appropriately. Treatment should be reviewed regularly by a healthcare professional to ensure continued benefit.

Directions

Please refer to the medication’s patient information leaflet before starting any new medication.

  • Apply a thin layer of Protopic 0.1% Ointment to the affected areas twice daily.

  • Continue treatment until the eczema has cleared.

  • For maintenance, apply twice weekly to prevent flare-ups.

  • Wash hands after application unless treating the hands.

  • Avoid bathing, showering, or swimming immediately after application.

Store below 25°C. Keep in original packaging and out of reach of children.

Ingredients

Active Ingredient:

  • Tacrolimus monohydrate 0.1% w/w

Other Ingredients:

  • White soft paraffin

  • Liquid paraffin

  • Propylene carbonate

  • White beeswax

  • Hard paraffin

Side Effects

Common side effects may include:

  • Burning sensation at the application site

  • Itching

  • Redness

  • Skin tingling

Serious (rare) side effects:

  • Skin infections

  • Swollen lymph nodes

  • Photosensitivity reactions

Stop the medicine and seek medical attention if serious side effects occur.

Warnings

  • Allergies: Do not use if allergic to tacrolimus or any other ingredients.

  • Pregnancy and Breastfeeding: Consult your doctor before use.

  • Medical Conditions: Not suitable for individuals with weakened immune systems or certain skin conditions.

  • Age Restrictions: Not recommended for children under 16 years.

  • Drug Interactions: Inform your doctor of all medications you are taking.

How often should I apply Protopic 0.1% ointment?

At first, you apply Protopic 0.1% ointment twice daily, then reduce to maintenance use if advised by your doctor.

Yes, Protopic 0.1% ointment is safe for sensitive areas like the face, neck, and folds.

Yes, you should protect skin treated with Protopic 0.1% ointment from sunlight and UV lamps.

Protopic 0.1% ointment is usually prescribed for adults, but lower strengths may be used for children under supervision.

Protopic 0.1% ointment mainly treats moderate to severe eczema, especially where steroids are unsuitable.

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