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Rabeprazole GR Tablets

Rabeprazole is a prescription-only treatment for acid reflux, ulcers, and other gastrointestinal conditions.

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Rabeprazole is a prescription-only medication used to treat gastrointestinal conditions related to high levels of stomach acid. It is commonly prescribed for patients suffering from gastro-oesophageal reflux disease (GORD), duodenal or gastric ulcers, and other acid-related disorders. Rabeprazole is also used in combination with antibiotics to treat Helicobacter pylori infections. It offers effective and targeted symptom relief for patients with both short-term and chronic digestive issues.

How It Works

Rabeprazole belongs to a class of medicines called proton pump inhibitors (PPIs). It works by irreversibly blocking the H+/K+ ATPase enzyme system—commonly known as the proton pump—in the gastric parietal cells. This enzyme is responsible for producing stomach acid. By inhibiting this system, Rabeprazole significantly reduces acid secretion, allowing the oesophagus, stomach, and duodenal lining to heal from irritation or ulcers caused by acid exposure. This results in a reduction in symptoms such as heartburn, indigestion, and acid reflux, and helps prevent damage to the gastrointestinal tract.

Why Choose Rabeprazole

Rabeprazole provides long-lasting acid suppression and symptom control with once-daily dosing, making it a convenient treatment for acid-related conditions. It is typically well tolerated and effective for both rapid symptom relief and long-term management. Many patients experience significant improvement in discomfort within days of starting treatment. Rabeprazole is also a key component in eradication therapy for Helicobacter pylori when combined with antibiotics. Its consistent and predictable acid suppression makes it a trusted option among prescribers.

Important Note

Rabeprazole should only be used under medical supervision. It is not intended for occasional or short-term indigestion relief without a diagnosis. Long-term use of PPIs may be associated with certain risks, including vitamin B12 deficiency, magnesium imbalance, and increased fracture risk. Regular monitoring may be necessary during extended treatment. Rabeprazole should not be abruptly discontinued without medical guidance. It is also important to report any new or unusual symptoms such as persistent diarrhoea, unexplained weight loss, or difficulty swallowing.

Directions

Please refer to the medication’s patient information leaflet before starting any new medication.

  • Take Rabeprazole once daily, usually before food, as directed by your healthcare provider.

  • Swallow the tablet whole with water—do not crush or chew.

  • Take at the same time each day for best results.

  • Do not exceed the prescribed dose.

  • If a dose is missed, take it as soon as you remember unless it is close to the next scheduled dose.

Store below 25°C. Keep in original packaging and out of reach of children.

Ingredients

Active Ingredient:

  • Rabeprazole sodium (typically 10mg or 20mg per tablet)

Other Ingredients:

  • Magnesium oxide

  • Mannitol

  • Hydroxypropyl cellulose

  • Ethylcellulose

  • Titanium dioxide

  • Other tablet coating agents

Side Effects

  • Common side effects may include:

    • Headache

    • Nausea

    • Abdominal pain

    • Diarrhoea

    • Flatulence

    Serious (rare) side effects:

    • Severe allergic reaction

    • Low magnesium levels (muscle cramps, irregular heartbeat)

    • Liver problems

    • Bone fractures (with long-term use)

    • Persistent diarrhoea

    Stop the medicine and seek medical attention if serious side effects occur.

Warnings

  • Allergies: Do not take Rabeprazole if you are allergic to rabeprazole or any of the tablet’s ingredients.

  • Pregnancy and Breastfeeding: Use only under medical supervision if pregnant or breastfeeding.

  • Medical Conditions: Use with caution in people with liver disease or osteoporosis risk.

  • Age Restrictions: Suitable for adults only, unless otherwise advised by a healthcare professional.

  • Drug Interactions: Inform your doctor if you are taking antifungals, blood thinners, HIV medicines, or digoxin.

Can I take Rabeprazole with other medications?

Some medications may interact with Rabeprazole. Always inform your doctor about any other medicines or supplements you are taking, including antifungals, blood thinners, or HIV treatments.

Rabeprazole is a proton pump inhibitor (PPI). It blocks the enzyme in the stomach lining that produces acid, thereby reducing the amount of acid present and helping to relieve symptoms and allow healing.

Take Rabeprazole once daily, usually before a meal. Swallow the tablet whole with water—do not crush, chew, or split it. Follow your prescriber’s instructions for best results.

Rabeprazole may not be suitable for people with certain liver conditions, low magnesium levels, or those taking specific medications. A medical assessment is required before starting treatment.

Rabeprazole is used to treat conditions caused by excessive stomach acid, including gastro-oesophageal reflux disease (GORD), stomach ulcers, and Zollinger-Ellison syndrome.

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