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Weight Loss
Wegovy® tablets are a once-daily oral weight loss treatment containing semaglutide. Now MHRA-approved for weight management in the UK, they offer a convenient, needle-free alternative to weekly weight loss injections.
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Wegovy® (semaglutide) is a prescription-only weight loss treatment developed by Novo Nordisk. Until recently, semaglutide was only available as a weekly injection. The tablet form offers the same active ingredient in a once-daily pill, making it a practical option for adults who prefer to avoid injections.
Semaglutide works by mimicking a naturally occurring hormone called GLP-1 (glucagon-like peptide-1). This hormone is released after eating and plays a key role in regulating appetite and blood sugar levels. By activating GLP-1 receptors in the brain, Wegovy® helps reduce hunger, increase feelings of fullness, and lower overall calorie intake.
Wegovy® tablets are intended to be used alongside a reduced-calorie diet and increased physical activity as part of a structured weight management programme. They are prescribed where clinically appropriate following a full medical assessment.
Wegovy® tablets have been approved by the MHRA for weight loss in the UK. They are currently only available via private prescription.
Like all medicines, Wegovy® tablets can cause side effects. Most are mild to moderate and tend to improve as your body adjusts to the medication, particularly during the dose-increase phase.
Common side effects include:
Serious side effects — seek medical advice promptly if you experience:
This is not a full list of side effects. Read the patient information leaflet supplied with your medication and speak to your prescriber or pharmacist if you have any concerns.
Wegovy® tablets are not suitable for everyone. Do not take this medication if you:
Tell your prescriber before starting Wegovy® tablets if you:
Wegovy® tablets are a prescription-only medicine and are only prescribed following a full clinical assessment. Always follow the guidance of your prescriber and read the patient information leaflet before use.
Both the tablet and the injection contain the same active ingredient, semaglutide. The key difference is how they are taken: the injection is given once a week, while the tablet is taken once daily. The tablet must be taken on an empty stomach with strict timing rules to ensure it is absorbed properly.
Results vary between individuals. Wegovy® works gradually as your dose is increased over several months. Clinically meaningful weight loss is typically seen over a period of weeks to months when used consistently alongside diet and lifestyle changes.
Wegovy® tablets are used for chronic weight management in adults with obesity, or in adults who are overweight and have at least one weight-related health condition such as high blood pressure, high cholesterol, or type 2 diabetes. They are used alongside a reduced-calorie diet and increased physical activity.
There are no specific foods to avoid, but the tablet must be taken on a completely empty stomach. Food consumed before or too soon after taking the tablet significantly reduces how well the medication is absorbed. Follow the 30-minute waiting rule strictly.
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Prescription weight-loss treatments are licensed medicines and may cause side effects. ALUNA's clinicians will discuss all risks and alternatives with you before prescribing. Our service does not replace emergency care or your NHS GP.