Malarone Paediatric Tablets are a prescription-only antimalarial medicine used to protect children aged 11kg to 40kg against malaria, specifically Plasmodium falciparum infection. Malaria is a serious mosquito-borne disease common in many tropical and subtropical countries.
Malarone Paediatric is particularly effective for short-term travel to regions with a high risk of drug-resistant malaria. The tablets combine two active ingredients—atovaquone and proguanil hydrochloride—which work together to stop the parasite’s lifecycle in the body.
How It Works
The active ingredients disrupt essential biological functions in the malaria parasite:
Atovaquone interferes with mitochondrial function within the parasite
Proguanil inhibits folic acid synthesis needed for parasite DNA replication
This dual action provides highly effective protection against malaria and prevents the development of resistance when taken as directed.
Why Choose Malarone Paediatric Tablets
These tablets are widely recommended by NHS travel clinics and GPs for paediatric malaria prophylaxis. They offer dependable protection and a short post-travel dosing period compared to older alternatives.
Benefits include:
Trusted paediatric malaria prevention
Child-friendly dosage based on body weight
Once-daily administration
Short 7-day post-travel treatment
Effective in regions with chloroquine resistance
Malarone Paediatric is also more palatable and easier to crush or mix into food, making it convenient for younger children.
Important Note
Begin taking Malarone Paediatric 1–2 days before entering a malaria area. Continue throughout the stay and for 7 days after leaving. Ensure all doses are taken consistently each day. If vomiting occurs within 1 hour of dosing, repeat the dose.
Directions
Note: Follow your GP’s dosing schedule and weight-based instructions.
Storage:
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Ingredients
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Side Effects
Common side effects:
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Headache
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Stomach pain
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Nausea or vomiting
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Diarrhoea
Rare but serious:
Seek immediate medical help for signs of allergic reaction or persistent symptoms.
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Warnings
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Contraindications:
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Allergy to any component
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Severe renal impairment
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Pregnancy/Breastfeeding:
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Drug Interactions:
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Age/Weight Restrictions:
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Start 1 to 2 days before travel and continue daily during the stay. Keep taking it for 7 days after leaving the malaria area.
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If vomiting occurs within 1 hour, give another dose immediately. If vomiting continues, consult a doctor.
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Some medicines, such as antibiotics, HIV treatments, and blood thinners, may interfere with Malarone Paediatric. Always check with a doctor first.
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Yes, it’s important to use insect repellent, wear protective clothing, and sleep under a treated mosquito net.
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Yes, the tablet can be crushed and mixed with food or a milky drink to make it easier to take.
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