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Metronidazole 400mg Tablets

Metronidazole is an antibiotic used to treat bacterial and protozoal infections including dental, vaginal, and gastrointestinal conditions.

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Metronidazole 400 mg is a prescription-only antibiotic used to treat Bacterial Vaginosis (BV), a common condition caused by an imbalance in the natural bacteria found in the vagina. BV can lead to symptoms like unusual vaginal discharge, a fishy odour, irritation, and discomfort. Metronidazole works internally to clear the infection and restore healthy balance — often within just a few days of starting treatment.

How It Works

Metronidazole belongs to a group of antibiotics that target anaerobic bacteria — the type that thrive in low-oxygen environments like the vagina during BV. The medicine disrupts these bacteria’s ability to grow and reproduce by damaging their DNA. As a result, harmful bacteria are eliminated while allowing beneficial bacteria to return, helping restore a healthy vaginal environment.

The 400 mg tablet is typically taken twice daily for five to seven days. Because the medication is absorbed into your system, it treats the infection throughout the body, not just at the surface. This approach ensures a more complete and lasting result.

Why Choose Metronidazole

Metronidazole is the first-line treatment for BV and is trusted by GPs and sexual health clinics across the UK. It offers a convenient oral alternative to vaginal gels or creams, especially for people who prefer tablets. With proven effectiveness, rapid results, and broad usage history, it’s a reliable solution for many women.

The treatment is discreet, easy to follow, and generally well tolerated. When taken as directed, most people experience full relief without needing additional medications.

Important Note

Avoid alcohol during the course and for 48 hours after the last dose — combining the two can lead to severe nausea, vomiting, and flushing. Always finish the full course even if symptoms improve early, to avoid reinfection or resistance.

Directions

  • Please refer to the medication’s patient information leaflet before starting any new medication.

    • Take Metronidazole with or after food to reduce stomach upset

    • Follow the prescribed dose and duration exactly

    • Do not consume alcohol during treatment or for 48 hours after

    • Do not exceed the maximum prescribed daily dose

    • Store below 25°C

    • Keep in original packaging

    • Keep out of reach of children

Ingredients

Active Ingredient:

  • Metronidazole 400 mg

Other Ingredients:

  • Maize starch

  • Microcrystalline cellulose

  • Povidone

  • Magnesium stearate

  • Sodium starch glycolate

  • Hypromellose

  • Titanium dioxide

  • Macrogol

Side Effects

Common side effects may include:

  • Nausea

  • Metallic taste

  • Loss of appetite

  • Diarrhoea

  • Headache

Rare side effects:

  • Seizures

  • Peripheral neuropathy (tingling or numbness in limbs)

  • Severe allergic reaction (rash, swelling, breathing difficulties)

  • Liver dysfunction

  • Blood disorders

Stop the medicine and seek medical attention if serious side effects occur.

Warnings

Do not take Metronidazole if you are allergic to metronidazole or other nitroimidazole derivatives. Avoid alcohol during treatment and for at least 48 hours after the final dose. Use with caution in individuals with liver disease, epilepsy, or blood dyscrasias. Not recommended during the first trimester of pregnancy unless clearly necessary, and only under medical supervision during breastfeeding.

Can I take Metronidazole during pregnancy?

Metronidazole should be used during pregnancy only if clearly needed. Consult your doctor for advice specific to your situation.

No, you should avoid alcohol during treatment and for at least 48 hours after completing the course, as it can cause unpleasant side effects like nausea and vomiting.

Take the tablets exactly as prescribed by your doctor, usually with food to minimize stomach upset. Swallow the tablets whole with a glass of water.

Metronidazole 400mg is used to treat various bacterial and protozoal infections, including dental infections, bacterial vaginosis, trichomoniasis, and infections of the gastrointestinal tract.

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