Permethrin 5% Cream (Generic Lyclear)

Permethrin 5% Cream is a topical treatment containing permethrin, a synthetic pyrethroid that paralyses and kills mites and lice. It works by disrupting the sodium channels in their nerve cells, causing paralysis and eventual death.
Once applied to the entire body, Permethrin 5% Cream effectively targets Sarcoptes scabiei (scabies mites) and pubic lice. It also destroys eggs laid under the skin, preventing further infestation. Though mites are typically killed within a few hours, itching may persist due to the skin’s inflammatory response to mite debris.

Why Choose Permethrin 5% Cream

Permethrin 5% is the most commonly prescribed treatment for scabies and pubic lice in the UK. Key benefits include:
Fast-acting and highly effective

Suitable for all age groups, including babies over 2 months

Single application usually sufficient

Easy to apply across the full body

Minimal absorption into bloodstream

The cream is odourless, well-tolerated, and proven effective in clinical use. It’s often used in public health settings for controlling outbreaks of scabies in care homes and households.

Important Note

Permethrin 5% Cream should be used exactly as prescribed. Apply to clean, dry skin and leave on for 8–12 hours before washing off. Treat close contacts simultaneously to prevent reinfection. Avoid contact with eyes, mucous membranes, and broken skin. Always wash clothing, bedding, and towels in hot water after treatment. If symptoms persist or worsen after 14 days, consult your doctor. Itching may continue due to allergic irritation even after mites are eradicated — this is not a sign of treatment failure.