Utrogestan 100mg Capsules contain micronised progesterone, a natural hormone used to complement oestrogen in hormone replacement therapy (HRT). It is suitable for postmenopausal women who have not had a hysterectomy. When oestrogen is used alone in HRT, it can increase the risk of endometrial hyperplasia and cancer. Progesterone like Utrogestan helps protect the lining of the uterus.
Utrogestan is taken orally and is commonly prescribed alongside transdermal oestrogen products such as Oestrogel or Estradot.
How It Works
Progesterone plays a crucial role in the menstrual cycle and maintaining uterine health. Utrogestan mimics the body’s own progesterone. When taken cyclically or continuously, it ensures that oestrogen-induced endometrial growth is counteracted, lowering the risk of abnormal bleeding or hyperplasia.
Because the progesterone is micronised, it is more efficiently absorbed by the body when taken orally.
Why Choose Utrogestan
Utrogestan is the only body-identical oral progesterone licensed for use in HRT in the UK. Unlike synthetic alternatives (like medroxyprogesterone), it is well-tolerated by most women and has a lower side effect profile.
Key benefits include:
Natural, body-identical hormone
Reduced risk of breast tenderness and mood changes
No synthetic additives or preservatives
Effective protection of the endometrium during HRT
Used in both sequential and continuous HRT regimens
Many women prefer Utrogestan for its natural profile and suitability for a personalised HRT plan.
Important Note
This medication is taken orally, typically at bedtime. Do not crush or chew the capsules. You may experience temporary drowsiness, so avoid driving if affected. Regular HRT reviews and monitoring are recommended. Always take it as prescribed in conjunction with an oestrogen treatment.
Directions
Note: Always follow your doctor’s instructions and leaflet guidance.
Administration:
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Take with water, preferably on an empty stomach or at least 2 hours after food
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Take at bedtime to reduce drowsiness during the day
Storage:
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Ingredients
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Active Ingredient:
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Key Excipients:
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Side Effects
Common side effects:
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Drowsiness
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Breast tenderness
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Headache
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Bloating
Serious but rare:
Discontinue if you experience unusual vaginal bleeding, jaundice, or mood changes.
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Warnings
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Contraindications:
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Pregnancy/Breastfeeding:
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Drug Interactions:
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Monitoring:
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Most women begin to feel the benefits within a few weeks, but it can take up to three months for full effects.
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Take the capsules at bedtime on an empty stomach. This helps reduce drowsiness during the day.
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No — Utrogestan is only prescribed for women who still have their womb and are using oestrogen as part of HRT.
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Yes, it can. Taking it at night helps manage this side effect.
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It’s best taken without food. Eating before your dose can increase the risk of drowsiness.
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