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Prescription Only

Duac 10mg/g + 50mg/g

Duac Gel is a prescription acne treatment combining clindamycin and benzoyl peroxide to clear spots, reduce bacteria, and prevent blocked pores.Packaging and branding may differ from image shown.

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Reviewed by UK-registered prescribers
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Ongoing clinical support included
GPhC-registered pharmacy

Duac Gel is a topical prescription treatment for acne vulgaris in adolescents and adults. It is typically recommended for mild to moderate forms of acne involving blackheads, whiteheads, and inflamed spots. Its dual-action formula provides an effective approach to treating acne at its root causes, including bacterial infection, clogged pores, and inflammation.

How It Works
Duac contains two active ingredients: clindamycin (an antibiotic) and benzoyl peroxide (a keratolytic agent with antibacterial properties). Clindamycin works by stopping the growth of Propionibacterium acnes, the bacteria associated with acne. Benzoyl peroxide penetrates the skin and removes dead cells, unblocks pores, reduces sebum production, and helps prevent new breakouts. It also has its own antibacterial action, which reduces the likelihood of developing resistance to clindamycin.

Why Choose Duac Gel
Duac offers the convenience of a combined treatment in one application, simplifying acne care routines. It is clinically proven to reduce both inflammatory and non-inflammatory acne lesions. Users typically notice improvements within 2–5 weeks. The gel is lightweight, absorbs quickly, and can be used on the face, back, or chest. Its dual mechanism makes it particularly effective for patients who have not responded well to single-agent treatments.

Important Note
Duac Gel should only be used under medical supervision. It may bleach clothing, hair, or bedding, so care should be taken during and after application. It is not suitable for use on broken or sunburnt skin. Patients should avoid sunbeds and excessive sunlight exposure while using this medication. If no improvement is seen after 12 weeks or side effects occur, consult a healthcare provider.

Directions

Please refer to the medication’s patient information leaflet before starting any new medication.

  • Apply a thin layer to affected areas once daily in the evening

  • Use on clean, dry skin

  • Avoid eyes, mouth, and broken skin

  • Wash hands after application

  • Do not use with other topical acne treatments unless directed

  • Store in the refrigerator before dispensing

  • After opening, store below 25°C

  • Keep out of reach of children

Ingredients

Active Ingredients:

  • Clindamycin phosphate 1%

  • Benzoyl peroxide 5%

Other Ingredients:

  • Carbomer

  • Dimethicone

  • Glycerol

  • Purified water

  • Sodium hydroxide

  • Disodium edetate

Side Effects

Common side effects may include:

  • Dryness or peeling of the skin

  • Redness or irritation

  • Itching

  • Burning sensation

Serious (rare) side effects:

  • Severe allergic reaction (rash, swelling, difficulty breathing)

  • Diarrhoea or stomach pain (linked to antibiotic use)

  • Skin blistering or severe irritation

Stop the medicine and seek medical attention if serious side effects occur.

Warnings

Do not use Duac Gel if allergic to clindamycin, benzoyl peroxide, or lincomycin. Avoid contact with eyes, mouth, mucous membranes, and broken skin. Use with caution in those with sensitive skin. Do not use during pregnancy or breastfeeding unless advised by a doctor. Avoid sun exposure and UV light during treatment. Stop use if severe irritation develops or no improvement is seen after 12 weeks.

What is Duac used for?

Duac is used to treat acne by reducing bacteria, clearing pores, and calming inflamed skin.

Most people start to see results from Duac within 2 to 4 weeks of daily use.

Yes, moisturising daily can help reduce dryness and keep your skin barrier healthy.

Yes, Duac is a prescription-only gel and should be used under medical supervision.

Yes, Duac may bleach clothing, pillowcases, and towels. Let it dry fully before contact with fabric.

How It Works

How it works

No GP appointment needed. Five simple steps to get your treatment delivered.

1

Start Consultation

Begin your online consultation by answering a short medical questionnaire about your health.

2

Choose Treatment

Select your preferred treatment from our range of clinically-approved options.

3

Prescribe

Our UK-registered prescriber reviews your consultation and issues a prescription if appropriate.

4

Review

Our pharmacist clinically checks your prescription and dispenses your medication safely.

5

Delivered to Your Door

Your medication is dispatched in discreet packaging with next-day delivery available.

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